Abstract
WITH the assistance of Mr. R. G. C. Jenkins and Miss C. Fischmann, we have now fully confirmed the theory suggested previously that the ultra-violet irradiation of ergosterol produces three substances in succession (Webster and Bourdillon, Biochem. J., 22, 1223; 1928: J. Soc. Chem. Ind., 47, 1059; 1928). Of these, the first shows intense absorption for wavelengths between 2500 A. and 2900 A., and great, anti-raehitie power. The second shows intense absorption at 2400 A., and no antirachitic power. The final product (or products) has little or no appreciable absorption and no antirachitic power. We are now convinced that the first substance is vitamin D, for the following reasons:
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WEBSTER, T., BOURDILLON, R. The Absorption Spectrum of Vitamin D. Nature 123, 244 (1929). https://doi.org/10.1038/123244a0
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DOI: https://doi.org/10.1038/123244a0