Abstract
EXPERIMENTS previously reported1, 2, 5, 6 on the effect of gonad-stimulating hormones in hypophysectomised animals have yielded somewhat contradictory results, probably because the number of animals studied has never been large. One of us (H. S.) has recently hypophysectomised more than six hundred albino rats by a modification of the Smith technique, by means of which it has been possible to complete the operation within five minutes, with unusually low immediate mortality, and we wish to present here a preliminary report of our findings.
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References
Smith, Amer. J. Anat., 45, 205; 1930.
Wallen-Lawrence and Van Dyke, J. Pharmacol., 43, 93; 1931.
Collip, Thomson, McPhail and Williamson, Can. Med. Assn. J., 24, 201; 1931.
Noguchi, Jap. J. Med. Sci. Pharmacol., 5, 104; 1931.
Evans, et. al., Amer. J. Physiol., 100, 141; 1932.
Freud, Deutsch. med. Woch., 58, 974; 1932.
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COLLIP, J., SELYE, H. & THOMSON, D. Gonad-Stimulating Hormones in Hypophysectomised Animals. Nature 131, 56 (1933). https://doi.org/10.1038/131056a0
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DOI: https://doi.org/10.1038/131056a0
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