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Supposed Direct Spectroscopic Observation of the “Oxygen-Transporting Ferment"

Abstract

THE supposition as to the hæmatin nature of oxidase (or Warburg oxygen transporting ferment) has been based so far only on the photochemical absorption spectrum obtained from the study of the effect of light, of definite energy and different wavelengths, on the oxygen uptake of cells poisoned with carbon monoxide. The concentration of the oxidase in cells is supposed to be too low for the direct spectroscopic observation of this enzyme even in the actively respiring yeast cells1.

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References

  1. Warburg, O., and Kubowitz, F., Bioch. Z., 203, 95; 1928.

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  2. Warburg, O., and Negelein, E., ibid., 262, 237; 1933.

  3. Kubowitz, F., and Haas, E., ibid., 255, 247; 1932.

  4. Yaoi, H., and Tamiya, H., Proc. Imp. Acad. Japan, 4, 436; 1928.

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  5. Fink, H., Z. physiol. Chem., 210, 197; 1932.

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KEILIN, D. Supposed Direct Spectroscopic Observation of the “Oxygen-Transporting Ferment". Nature 132, 783 (1933). https://doi.org/10.1038/132783a0

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