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Cancer and the Theory of Organisers

Abstract

THE fundamental fact about cancerous tissue is that it has escaped from the normal growth-controlling agents of the body. The escape often involves a change in histological type. The problems which are raised are clearly connected with those studied in experimental embryology, where again it is the causal mechanism underlying growth and histological change which is under investigation. Experimental embryology has recently made important advances, and the time has perhaps come when it would be profitable to consider the way in which the new embryological theories would formulate the well-known problems of cancer research.

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WADDINGTON, C. Cancer and the Theory of Organisers. Nature 135, 606–608 (1935). https://doi.org/10.1038/135606a0

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