Abstract
RECENTLY it has been shown that phloridzin exerts an inhibitory effect on phosphorylations and dephosphorylations1. The action on enzymes other than diastase has not yet been investigated. On diastase no poisonous action of phloridzin was demonstrable1,2; however, phloridzin is not a specific inhibitor of phosphorylation and dephosphorylation. As the present communication shows, the dismutative conversion of triosephosphoric acid into phosphoglyceric acid and glycerophosphoric acid is also prevented or markedly inhibited by phloridzin in concentrations of about N/100.
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References
Lundsgaard, Biochem. Z., 264, 209; 1933.
Barth, Biochem. Z., 270, 63; 1934.
Meyerhof and Lohmann, Biochem. Z., 271, 89; 1934.
Meyerhof and Kiessling, Biochem. Z., 279, 40; 1935.
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KALCKAR, H. Inhibitory Effect of Phloridzin on an Enzymic Dismutation. Nature 136, 872–873 (1935). https://doi.org/10.1038/136872c0
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DOI: https://doi.org/10.1038/136872c0
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