Abstract
IN examining C hypovitaminosis we found a patient, suffering from paroxysmal (cold) hæmoglobinuria, highly deficient in ascorbic acid. The patient was treated with ascorbic acid, 300 mgm. being given intravenously for several days. The hæmoglobinuria, easily elicited before, disappeared. Though the treatment was stopped more than six weeks ago, no paroxysm can now be stimulated. The protective action of ascorbic acid on red blood corpuscles could also be demonstrated in vitro. We think this experience justifies a trial with ascorbic acid in blackwater fever.
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ARMENTANO, L. Ascorbic Acid in Paroxysmal Hæmoglobinuria. Nature 137, 910 (1936). https://doi.org/10.1038/137910a0
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DOI: https://doi.org/10.1038/137910a0
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