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The Structure of Aneurin and Thiochrome

Abstract

R. R. WILLIAMS has just published1 a note on the structure of aneurin (vitamin B1). From a study of degradation products of the vitamin, he concludes that his original formula (I)2 for aneurin is wrong, and that it should be represented by (II: where R1 = CH3; R2 = H); this new structure is similar in essentials to that suggested on theoretical grounds by K. Makino and T. I. Imai (II: where R1 = H; R2 = CH3)3.

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References

  1. J. Amer. Chem. Soc., 58, 1063 (1936).

  2. J. Amer. Chem. Soc., 57, 229 (1935).

  3. Z. physiol. Chem., 239, I (Feb. 28, 1936).

  4. G. Barger, F. Bergel and A. R. Todd, B., 68, 2257 (1935).

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BERGEL, F., TODD, A. The Structure of Aneurin and Thiochrome. Nature 138, 76 (1936). https://doi.org/10.1038/138076a0

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