Table 1 Means, Standard Deviations and Analysis of Variance Results for Eye Movement Measures
Placebo Day | Ketamine Day | |||||
---|---|---|---|---|---|---|
Target Velocity | Baseline | Infusion | Baseline | Infusion | F,P df for Phase by Drug | |
Closed Loop Condition | ||||||
Pursuit Gain 1 | 9.4 | .859 ± .088 | .895 ± .091 | .882 ± .087 | .769 ± .130 | 13.51 .004 1,11 |
18.7 | .887 ± .089 | .803 ± .102 | .810 ± .078 | .663 ± .102 | ||
Mask During the Ramp | ||||||
Mean Gain 2 | 9.4 | .617 ± .173 | .692 ± .156 | .649 ± .117 | .506 ± .194 | 9.48 .011 1,11 |
18.7 | .611 ± .114 | .642 ± .154 | .670 ± .171 | .503 ± .183 | ||
Residual Predictive Gain 3 | 9.4 | .503 ± .119 | .524 ± .172 | .564 ± .111 | .482 ± .089 | 2.70 .128 1,11 |
18.7 | .454 ± .100 | .468 ± .102 | .428 ± .076 | .409 ± .126 | ||
Mask at Beginning of Ramp | ||||||
Peak Gain 4 | 9.4 | .717 ± .237 | .754 ± .247 | .616 ± .189 | .673 ± .218 | .01 .941 1,11 |
18.7 | .596 ± .131 | .560 ± .186 | .582 ± .171 | .535 ± .163 | ||
Initiation Measures | ||||||
Open Loop Acceleration 7 | 9.4 | 59.42 ± 25.8 | 65.6 ± 21.2 | 61.3 ± 17.7 | 43.5 ± 14.3 | 5.66 .037 1,11 |
18.7 | 61.6 ± 31.3 | 57.2 ± 19.5 | 63.1 ± 24.1 | 49.3 ± 21.8 | ||
Latency 5 | 9.4 | .127 ± 0.24 | .131 ± .025 | .161 ± .118 | .140 ± .026 | .067 .801 1,11 |
18.7 | .119 ± .016 | .129 ± .029 | .131 ± .042 | .135 ± .040 | ||
Open Loop Velocity 6 | 9.4 | .362 ± .185 | .371 ± .153 | .340 ± .125 | .302 ± .127 | .039 .847 1,11 |
18.7 | .152 ± .079 | .169 ± .083 | .167 ± .064 | .155 ± .074 |