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The Biology of Crossing-over

Abstract

SEXUAL reproduction consists of two alter-nating processes: fertilization, by which two germ cells containing each a single set of chromosomes fuse and produce a zygote with the double number of chromosomes, and meiosis, by which the double number is reduced and germ cells are again formed with the single number. As Weismann first pointed out, the biological importance of these processes is that they enable the hereditary differences between the chromosomes to be recombined in the greatest number of ways to give the greatest number of different individuals and therefore the greatest scope for natural selection to act in directing evolutionary change.

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References

  1. Muller, H. J., and Prokofyeva, A. A., Proc. Nat. Ac. Sci., 21, 16–26 (1935).

    Article  ADS  CAS  Google Scholar 

  2. Darlington, C. D., J. Genet., 31, 185–212 (1935).

    Article  Google Scholar 

  3. Darlington, C. D., “Recent Advances in Cytology” (London, 1937).

    Google Scholar 

  4. Koller, P. C., Proc. Roy. Soc. Edin., 57, 194–214 (1937).

    Article  Google Scholar 

  5. Fisher, R. A., “The Genetical Theory of Natural Selection” (Oxford, 1930).

    Book  Google Scholar 

  6. Muller, H. J., Amer. Nat., 66, 118–138 (1932).

    Article  Google Scholar 

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Darlington, C. The Biology of Crossing-over. Nature 140, 759–761 (1937). https://doi.org/10.1038/140759a0

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