Abstract
EXPERIMENTS on the recovery of synthetic œstrogenic compounds related to stilbene and diphenylethane1 from the urine of female rabbits have shown that the recoveries are very high compared with that of œstrone under the same conditions2. Compounds such as 4:4′-dihydroxy-γ : δ-diphenyl-n-hexane and 4:4′-dihydroxy-α : β-diethylstilbene give recoveries of the order of 20 per cent compared with 1.5 per cent found for œstrone. This indicates a metabolic process for the synthetic œstrogens different from that of œstrone.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Dodds, E. C., Golberg, L., Lawson, W., and Robinson, Sir R., Proc. Roy. Soc., B, 127, 140 (1939).
Stroud, S. W., J. Endocrin., 1.
Dodds, E. C., Fitzgerald, M. E. H., and Lawson, W., NATURE, 140, 772 (1937).
Dodds, E. C., and Lawson, W., NATURE, 139, 627 (1937).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
STROUD, S. Preliminary Investigation of the Metabolism of Stilbene. Nature 144, 245 (1939). https://doi.org/10.1038/144245a0
Issue date:
DOI: https://doi.org/10.1038/144245a0
This article is cited by
-
Polyhydroxylated metabolites oftrans-stilbene in the rat
Experientia (1974)
