Abstract
VITAMIN B61 has been defined2 as “that part of the vitamin B2 complex which is responsible for the cure of the specific dermatitis developed by young rats fed on a vitamin B-free diet supplemented with purified vitamin B1 and lactoflavin” (riboflavin). The specific skin lesions (‘rat acrodynia’) are characterized by symmetrical dermatitis with œdematous, scaly skin, mainly on the most peripheral parts of the body, such as the mouth, nose, paws, ears and tail.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Gyrgy, P., Nature, 133, 493 (1934).
Birch, T. W., and Gyrgy, P., Biachem. J., 30, 301 (1936).
Lepkovsky, S., Jukes, T. H., and Krause, M. E., J. Biol. Chem., 115, 557 (1936).
Elvehjem, C. A., and Kochn, C. J., jun., J. Biol. Chem., 108, 709 (1935); Lepkovsky, S., and Jukes, T. H., ibid., 114, 109 (1936).
Kuhn, R., and Wendt, G., Ber. deulsch. chem. Gesell., 71, 780 (1938).
Gygy, P., J. Amer. Chem. Soc., 60, 933 (1933).
Oleson, J. J., Bird, H. R., Elvehjem, C. A., and Hart, E. B., J. Biol. Chem., 127, 23 (1939).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GYÜRGY, P., ECKARDT, R. Vitamin B6 and Skin Lesions in Rats. Nature 144, 512 (1939). https://doi.org/10.1038/144512a0
Issue date:
DOI: https://doi.org/10.1038/144512a0
This article is cited by
-
Weekly fluorouracil and high-dose leucovorin: efficacy and treatment of cutaneous toxicity
Cancer Chemotherapy and Pharmacology (1990)
-
Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with continuous 5-fluorouracil infusion
Investigational New Drugs (1990)
-
Difficulties in vitamin B6 nomenclature
Experientia (1968)
-
Effects of different vegetable fats on the cardiac damage caused by pyridoxine deficiency
Experientia (1959)
