Abstract
Two of us (R.A.A. and J.H.M.) have made many unsuccessful attempts to infect mice, guinea pigs, rabbits, hamsters, hedgehogs, and chicks with blue-tongue virus. Mice and guinea pigs were not rendered susceptible by blockading the reticulo-endothelial system with India ink, by deep X-ray therapy, or by maintenance on a vitamin-deficient diet of auto-claved oats. Finally no multiplication occurred in normal developing chick embryos when virus was seeded on the chorio-allantoic membrane, or in the yolk-sac (method of Cox, 1938).
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References
Cox, H. R., Pub. Hl. Rept., 53, 2241–47 (1938).
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MASON, J., COLES, J. & ALEXANDER, R. Cultivation of Bluetongue Virus in Fertile Eggs produced on a Vitamin-deficient Diet. Nature 145, 1022 (1940). https://doi.org/10.1038/1451022a0
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DOI: https://doi.org/10.1038/1451022a0
