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Nature of the Feulgen Reaction with Nucleic Acid

Abstract

MR. SEMMENS' “suggestion” that purines available in hydrolysed chromatin might be responsible for Feulgen staining was quite clear to us, and it was to test it that we re-examined the behaviour of certain purines with the Feulgen reagent. Since these experiments were a repetition of Semmens', their bearing on the point in question should be sufficiently clear to him. We consider his suggestion untenable because our tests, contrary to his, show that purines do not give any colour with the Feulgen reagent.

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BARBER, H., PRICE, J. Nature of the Feulgen Reaction with Nucleic Acid. Nature 146, 808 (1940). https://doi.org/10.1038/146808b0

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