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Ovarian Damage in Mature Baboons Produced by Progesterone and Astradiol Benzoate

Abstract

IT has been repeatedly shown1 that the administration of progesterone in amounts of 15–20 mgm. to normal adult baboons in the first part of the cycle (eighth-tenth day) will cause the turgescent perineum to undergo deturgescence, and premature bleeding supervenes within 5–8 days of the last injection. Any quantity of progesterone more than 3 mgm. and less than 15 mgm. will only cause perineal deturgescence.

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  1. Gillman, Joseph, Endocrinology, 26 80, 434 (1940).

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GILLMAN, J. Ovarian Damage in Mature Baboons Produced by Progesterone and Astradiol Benzoate. Nature 147, 575–576 (1941). https://doi.org/10.1038/147575b0

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