Abstract
IN 1938, Dodds, Goldberg, Lawson, and Robinson1 compared the carbon skeleton of 4: 4'–dihydroxy–α: β–diethylstilbene (stilbœstrol) with those of œstrone and chrysene. The similarities in molecular architecture may be significant. If this be so, the possibility arises that the α: β–diethylstilbene molecule might have a similar significance in the realm of synthetic, as the condensed ring system has in the natural, sex hormones.
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References
Dodds, E. C., Goldberg, L., Lawson, W., and Robinson, R., NATURE, 141, 247 (1938).
Linnell, W. H., and Roushdi, I. M., Quart. J. Pharm. Pharmacol., 12, 252 (1939).
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LINNELL, W., ROUSHDI, I. Synthetic Compounds Possessing Biological Activity Similar to that of Deoxycorticosterone. Nature 148, 595 (1941). https://doi.org/10.1038/148595a0
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DOI: https://doi.org/10.1038/148595a0
