Abstract
THE method of administration of sex hormones by subcutaneous implantation of compressed tablets, first described by Deanesly and Parkes1, is superior to regular injections in that the tablet, at least for some time, is slowly and continuously absorbed and supplies a relatively constant 'physiological' dosage of hormone.
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References
Deanesly, R., and Parkes, A. S., Proc. Roy. Soc., B, 124, 279 (1937).
Emmens, C. W., Endocrinology, 28, 633 (1941).
Forbes, T. R., Endocrinology, 29, 70 (1941).
Parkes, A. S., and Young, F. G., J. Endocrinology, 1, 108 (1939).
Folley, S. J., Scott Watson, H. M., and Bottomley, A. C., J. Dairy Res. 12, 241 (1941).
Geist, S. H., Walter, R. I., and Salmon, U. J., Proc. Soc. Exp. Biol, N.Y., 43, 712 (1940).
Foss, G. L., J. Endocrinology, 3, 107 (1942).
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FOLLEY, S. 'Ghost' Formation in Subcutaneously Implanted Tablets of Synthetic Œstrogens. Nature 150, 403–404 (1942). https://doi.org/10.1038/150403a0
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DOI: https://doi.org/10.1038/150403a0
