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A Serum that Discloses the Genotype of some Rh-Positive People

Abstract

THE blood-group antigen Rh, present in the red blood cells of about 85 per cent of normal people, called Rh-positive, and absent in the rest, Rh-negative, plays, with its corresponding anti-Rh agglutinin, an important part in the causation of erythroblastosis fœtalis, a familial disease of the new-born. In about 90 per cent of cases of the disease the mother is Rh-negative and has made anti-Rh which passes through the placenta and damages the red blood cells of her Rh-positive fœtus. The Rh factor is inherited as a dominant character with three genotypes RhRh, Rhrh and rhrh.

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RACE, R., TAYLOR, G. A Serum that Discloses the Genotype of some Rh-Positive People. Nature 152, 300 (1943). https://doi.org/10.1038/152300a0

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