Abstract
THE oxidation of acetate by mammalian tissue in vitro has been demonstrated; but comparatively little is known concerning the pathway of its oxidation or the possibility of its oxidation being coupled with phosphorylation. Recently Barcroft, McAnally and Phillipson1 showed that acetate maintained the beat of the perfused rabbit's heart. Their demonstration suggests the ability of acetate to furnish energy for the maintenance of function in this tissue.
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References
Barcroft, J. McAnally, R., and Phillipson, A., NATURE, 151, 304 (1943).
Lardy, H. A., and Phillips, P. H., Amer. J. Physiol., 133, 602 (1941); 134, 542 (1941).
Lardy, H. A., and Phillips, P. H., J. Biol. Chem., 149, 177 (1943).
Lardy, H. A., and Phillips, P. H., Amer. J. Physiol., 133, 741 (1943).
Lardy, H. A., and Phillips, P. H., J. Biol. Chem., 143, 333 (1943).
Breusch, F. L., Science, 97, 490 (1943).
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LARDY, H., PHILLIPS, P. Acetate Utilization for Maintenance of Motility of Bull Spermatozoa. Nature 153, 168–169 (1944). https://doi.org/10.1038/153168b0
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DOI: https://doi.org/10.1038/153168b0