Abstract
INTEREST in the inability of gelatin to act as a full antigen, that is, to produce specific anti-bodies when injected into an animal, has been revived by the observations of Haurowitz, Tunca and Schwerin1, and also by the suggested use of isinglass for blood transfusion2. Haurowitz et al. find that whereas the intravenous injection of arsanil-azo-globulin into rabbits leads to the deposition of the bulk of the arsenic in the liver and bone-marrow3, the injection of arsanil-azo-gelatin is followed by rapid excretion of the arsenic in the urine with very little deposition in the liver. The conclusions reached by these authors is that arsanil-azo-gelatin does not act as a full antigen because it is insufficiently deposited in the reticulo-endothelial cells of the body.
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WORMALL, A. Non-antigenicity of Gelatin. Nature 154, 332 (1944). https://doi.org/10.1038/154332a0
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DOI: https://doi.org/10.1038/154332a0
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