Abstract
IN 1942 we considered the possibility that strychnine has the constitution shown in (I), but were unable to find satisfactory explanations of all the transformation products on this basis. This difficulty is no longer insuperable, and in the light of new data and a critical review we now believe that the structure interprets the whole behaviour of strychnine better than any other.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Prelog and Szpilfogel, Experientia, 1, 197 (1945).
Robinson, R., Experientia, 2, 28 (1946).
Warnat, K., Helv. Chim. Acta, 14, 997 (1931). Blount, B. K., and Robinson, R., J. Chem. Soc., 2305 (1932); 595 (1934). Leuchs, H., Ber. deut. chem. Gesell, 70, 1543 (1937), and later papers.
Robinson, R., J. Chem. Soc., 111, 885 (1917).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
OPENSHAW, H., ROBINSON, R. Constitution of Strychnine and the Biogenetic Relationship of Strychnine and Quinine. Nature 157, 438 (1946). https://doi.org/10.1038/157438a0
Issue date:
DOI: https://doi.org/10.1038/157438a0
This article is cited by
-
Biosynthesis of strychnine
Nature (2022)
-
Synthesis and the Nobel Prize in Chemistry
Nature Chemistry (2017)
-
A view of progress in the chemistry of indole alkaloids
Experientia (1960)
-
Constitution of Strychnine and its Relation to Cinchonine
Nature (1947)
-
Oxidation of Neostrychnine
Nature (1947)
