Abstract
NACHMANSOHN and his colleagues1,2 and Feldberg and Mann3 have suggested the enzymatic synthesis of acetylcholine from choline and acetate in the presence of adenosine triphosphate. The alleged enzyme has been named choline acetylase. The authors used the m. rectus abdominis of frogs to test the quantity of synthetized acetylcholine.
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References
Nachmansohn, D., and Machado, A. L., J. Neurophysiol., 6, 397 (1943).
Nachmansohn, D., and John, H., J. Biol. Chem., 158, 157 (1945).
Feldberg, W., and Mann, T., J. Physiol., 104, 8 (1945).
Babsky, E., Korenevsky, O., and Minajev, P., Bull. Biol. et Med. Exper. de l'URSS., 20, 34 (1945).
Binet, L., and Minz, B., C.R. Soc. Biol., 116, 107 (1934).
Bergami, G., Physiol. J. USSR., 24, 56 (1938).
Feldberg, W., J. Physiol., 103, 367 (1945).
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BABSKY, E., MINAJEV, P. Sensitization of Muscle to Choline and Acetylcholine, and the Supposed Existence of Choline Acetylase. Nature 158, 268 (1946). https://doi.org/10.1038/158268b0
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DOI: https://doi.org/10.1038/158268b0
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