Abstract
Many different views have been expressed concerning the chemical steps by which certain species of Aspergillus and of Penicillium convert glucose into citric acid. Some of the earlier hypotheses are now only of historical interest, and those modern views for which a reasonable amount of experimental support can be adduced have one feature in common, namely, the presumption that acetic acid is an essential intermediate. Up to the present time, however, the occurrence of this acid in cultures of A. niger on sugar does not appear to have been demonstrated. We have made many attempts to detect its presence in the metabolism solution, but without success, an outcome not entirely unexpected in view of the ease with which A. niger metabolizes acetic acid in the presence of sugar (compare Pfeffer1).
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References
Pfeffer, Jahrb. wiss. Bot., 28, 205 (1895).
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CHUGHTAI, I., PEARCE, A. & WALKER, T. Detection of Acetic Acid in A. niger Growing on a Glucose Medium. Nature 160, 573 (1947). https://doi.org/10.1038/160573a0
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DOI: https://doi.org/10.1038/160573a0