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Nature of the C/D-ring Union in the Å’strogenic Hormones

Abstract

IN a recent discussion1 of the nature of the C/D-ring union in the natural Å"strogenic hormones (+)-œstrone and (+)-equilenin, I suggested that the stereochemical correspondence of these compounds was not beyond all doubt. It has since come to my notice that satisfactory evidence of such correspondence does, in fact, already exist in the literature. Because this evidence appears generally to have escaped recognition, it seems desirable to direct attention to it, and it is briefly summarized hereunder.

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SHOPPEE, C. Nature of the C/D-ring Union in the Å’strogenic Hormones. Nature 161, 207 (1948). https://doi.org/10.1038/161207a0

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