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Antibiotic Substances from the Heart Wood of Thuja plicata Don

Abstract

THE heart-wood of western red cedar (Thuja plicata Don.), which possesses a low specific gravity and is very resistant towards decay, has been examined by Anderson and Sherrard1. The steam distillate of this wood furnished an acid, C10H12O2, termed dehydroperillic acid, showing low toxicity, and a very toxic ‘phenol', m.p. 82°, of the same composition. For dehydroperillic acid they suggest the formula (I), but the structure of the compound of m.p. 82° was not elucidated.

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ERDTMAN, H., GRIPENBERG, J. Antibiotic Substances from the Heart Wood of Thuja plicata Don. Nature 161, 719 (1948). https://doi.org/10.1038/161719a0

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