Abstract
CATALASE is a hsematin enzyme found in relatively large concentrations in erythrocytes, liver, kidney, etc. Its extremely efficient catalysis of the destruction of hydrogen peroxide and its ability to catalyse the oxidation of alcohols by hydrogen peroxide have been recognized for some time, but very little direct evidence for the mechanisms of these reactions in terms of the theory of enzyme-substrate compounds has hitherto been obtained.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Amyloid-beta neuroprotection mediated by a targeted antioxidant
Scientific Reports Open Access 15 May 2014
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Hartridge, H., and Roughton, F. J. W., Proc. Roy. Soc., A, 104, 376 (1923).
Roughton, F. J. W., and Millikan, G. A., Proc. Roy. Soc., A, 155, 258 (1936).
Chance, B., Rev. Sci. Instr., 68, 601 (1947).
Stern, K. G., J. Biol. Chem., 114, 473 (1935).
Chance, B., Acta Chem. Scand., 1, 236 (1947); reactivity velocity constants at 25° C.
Theorell, H., Ark. Kemi. Min. o Geol., 16A, No. 3, 1 (1942).
Bonnichsen, R. K., Chance, B., and Theorell, H., Acta Chem. Scand. (in the press).
Chance, B., J. Biol. Chem., 151, 553 (1943).
Keilin, D., and Hartree, E. F., Proc. Roy. Soc., B, 119, 141 (1936).
Keilin, D., and Hartree, E. F., Biochem. J., 39, 293 (1945).
MacFayden, D. A., J. Biol. Chem., 158, 107 (1945).
Rieche, A., and Hitz., F., Ber., 62, 2458 (1929).
Stern, K. G., Z. physiol. Chem., 209, 176 (1932).
Lemberg, R., and Foulkes, E. C., Nature, 161, 131 (1948).
Agner, K., and Theorell, H., Arch. Biochem., 10, 321 (1946).
Sumner, J. B., "Adv. in Enz.", 1, 170 (1941).
George, P., Nature, 160, 41 (1947).
Theorell, H., Experientia (in the press).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CHANCE, B. The Enzyme-Substrate Compounds of Catalase and Peroxides. Nature 161, 914–917 (1948). https://doi.org/10.1038/161914a0
Issue date:
DOI: https://doi.org/10.1038/161914a0
This article is cited by
-
Amyloid-beta neuroprotection mediated by a targeted antioxidant
Scientific Reports (2014)
-
Kinetik und Wege des Methanolumsatzes
Naunyn-Schmiedebergs Archiv f�r Pharmakologie und Experimentelle Pathologie (1969)
-
Reactions of Hæmoproteins with Hydrogen Peroxide and the Supposed Formation of Hydrogen Peroxide During the Autoxidation of Hæmoglobin
Nature (1961)