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Interaction between Curare and the Potassium Ion at the Motor End Plate

Abstract

IN a previous paper1 evidence was presented that there is a relation between the curariform activity of an onium ion and the charge density on its quaternary central atom. A consideration of this theory and of the fact that the paralysing action of curare can be reversed by a fall of temperature2 led to an investigation of the antagonism between curare and the potassium ion3.

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References

  1. Holmes, P. E. B., Jenden, D. J., and Taylor, D. B., Nature, 159, 86 (1947).

    Article  ADS  CAS  Google Scholar 

  2. Holmes, P. E. B., Jenden, D. J., and Taylor, D. B., J. Physiol., 106, 21P (1947).

    Google Scholar 

  3. Quilliam, J. P., and Taylor, D. B., Nature, 160, 603 (1947).

    Article  ADS  CAS  Google Scholar 

  4. Bulbring, E., Brit. J. Pharmacol., 1, 38 (1946).

    CAS  PubMed  Google Scholar 

  5. Brown, G. L., and Feldberg, W., J. Physiol., 86, 290 (1936).

    Article  CAS  Google Scholar 

  6. Ing, H. R., and Wright, W. M., Proc. Roy. Soc., B, 109, 337 (1932).

    Article  ADS  Google Scholar 

  7. Eccles, J. C., Katz, B., and Kuffler, S. W., J. Neurophysiol, 5, 211 (1942).

    Article  CAS  Google Scholar 

  8. Fillenz, M., and Hanafin, M., J. Neurophysiol., 10, 189 (1947).

    Article  CAS  Google Scholar 

  9. Brown, G. L., J. Physiol., 91, 4P (1937).

    CAS  Google Scholar 

  10. Bacq, Z. M., and Brown, G. L., J. Physiol., 89, 45 (1937).

    Article  CAS  Google Scholar 

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HOLMES, P., JENDEN, D. & TAYLOR, D. Interaction between Curare and the Potassium Ion at the Motor End Plate. Nature 162, 217 (1948). https://doi.org/10.1038/162217a0

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