Yeast and Rickets

Abstract

USING purified enzyme preparations and certain samples of dried yeast, we have met with the same difficulties as has Dr. de Man in reproducing our first results. We found, however, that the inhibition increased the longer the duration of the experiment, and that the inhibition was considerable when rye bran and dried yeast were incubated together over-night before the adding of the substrate. Experiments show that phosphatases from the bran under these conditions split considerable amounts of inorganic phosphate from phosphoric acid compounds present in yeast. It seems to be this inorganic phosphate which is responsible for our finding of an inhibition of phytase by yeast.