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Antibiotic Activity as Shown by a Highly Amylolytic Strain of Bacillus subtilis

Abstract

IN the course of an investigation on the formation of amylase by Bacillus subtilis, it was observed that the organism, when grown on wheat bran medium, showed a pronounced antibiotic activity. The maximum activity was found in the aqueous extract from a 24-hour-old culture. The amylase formation during this period was found to be low, but steadily increased with further incubation. This phenomenon led to a study of the relationship between the antibiotic production and amylase formation by B. subtilis1 (N.C.T.C. : 2027 N) when grown on wheat bran.

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LULLA, B. Antibiotic Activity as Shown by a Highly Amylolytic Strain of Bacillus subtilis. Nature 163, 489 (1949). https://doi.org/10.1038/163489a0

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