Abstract
FOR some time now we have been using slide-culture of tubercle bacilli1 in Youmans medium2 as a direct method of testing streptomycin sensitivity of these organisms in sputum. The great advantage of this method over those previously described3–7 lies in its technical simplicity and rapidity. Giammalvo, Natsios and Elton8 have recently described the use of the slide-culture in this connexion ; but they worked with pure cultures requiring four to six weeks preparation and involving extensive manipulation of the culture. By contrast, using the method outlined below, a result can be obtained in seven days provided tubercle bacilli can be seen in the untreated specimen (sputum) by direct smear.
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Giammalvo, J. T., Natsios, G. A., and Elton, N. W., Amer. J. Clin. Path., 19, 76 (1949).
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RUBBO, S., WOODRUFF, P. & MORRIS, D. Association A Rapid Method of Determining Streptomycin Sensitivity of Mycobacterium tubercú ulosis. Nature 164, 313–314 (1949). https://doi.org/10.1038/164313a0
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DOI: https://doi.org/10.1038/164313a0
