Abstract
IT was previously shown that the secretion of both fructose and citric acid in the male accessory organs of reproduction is governed by, and responds readily to, the fluctuations in the level of the male sex hormone. This close relationship made it practical to use the estimation of fructose and citric acid, either in semen or in the accessory glands, as a 'chemical indicator test' for the male hormone1'2'3. Recently, in the course of a metabolic study of transplants from accessory glands of the rat, it was found that when small pieces of male glands were dissected from young rats and transplanted subcutaneously into male or female hosts, such transplants grew readily in response to testosterone propionate or normally secreted testis hormone, and when fully developed exhibited a high content of fructose and pitric acid4,5.
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References
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Price, D., Mann, T. & Lutwak-Mann, C. Some Metabolic Effects of Androgenic Substances. Nature 164, 950–951 (1949). https://doi.org/10.1038/164950a0
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DOI: https://doi.org/10.1038/164950a0
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