Abstract
A SERIES of potent analgesics, as active as morphine in the rat, has been discovered in the 3-tertiary-amino-1 : l-(2′-thienyl)-but-1-enes (I). The analgesic toxicity ratios are not greatly different from that of amidone (II; R = Me). 
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References
Attenburrow, J., Elks, J., Hems, B. A., and Speyer, K. N., J. Chem. Soc., 510 (1949).
Bergel, F., and Morrison, A. L., Quart. Rev., Chem. Soc., 2, 381 (1948).
Adamson, D. W., J. Chem. Soc., S 144 (1949).
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ADAMSON, D., GREEN, A. A New Series of Analgesics. Nature 165, 122 (1950). https://doi.org/10.1038/165122a0
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DOI: https://doi.org/10.1038/165122a0
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