Abstract
IT has been shown that when sugar and phosphate are unavailable, mitotic activity in the mouse is severely depressed. Such a depression develops rapidly after injections of insulin or phloridzin1 and during ischæmic shock2. In these circumstances the significant observation can be made that sudden sugar-lack has no effect on the completion of any mitosis already under way. It has been suggested that the great importance of sugar in cell division may be for the production of energy; but if this is correct it is also evident that such energy is required only at the very beginning of the process3.
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References
Bullough, W. S., J. Exp. Biol., 26, 83 (1949).
Bullough, W. S., and Green, H. N., Nature, 164, 795 (1949).
Bullough, W. S., J. Endocrinol, [6, 350 (1950)].
Bullough, W. S., Proc. Roy. Soc., B, 135, 212 (1948).
Medawar, P. B., Quart. J. Mic. Sci., 88, 27 (1947)
Bullough and Johnson (unpublished).
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BULLOUGH, W. Completion of Mitosis after Death. Nature 165, 493 (1950). https://doi.org/10.1038/165493a0
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DOI: https://doi.org/10.1038/165493a0
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