Abstract
THE existence of ‘incomplete’ forms of antibodies active against human erythrocytes and detectable by means of the Coombs test1 is now widely recognized. Rh antibodies are commonly present in this form, and so are some at least of the recently recognized rarer immune antibodies2, such as anti-Kell and anti-S. The fact that the iso-antibodies anti-A and anti-B may similarly exist in incomplete forms is also being increasingly realized3.
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References
Coombs, R. R. A., Mourant, A. E., and Race, R. R., Brit. J. Exp. Path., 26, 255 (1945).
Leading article, Lancet, July 16, 1949.
Witebsky, E., Blood, special issue No. 2, 66 (1948).
Levine, P., and Wigod, M., first meeting of the International Society of Hematology, Buffalo (1948).
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DACIE, J. Occurrences in Normal Human Sera of ‘Incomplete’ Forms of ‘Cold’ Auto–Antibodies. Nature 166, 36 (1950). https://doi.org/10.1038/166036a0
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DOI: https://doi.org/10.1038/166036a0
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