Order of Genes in the Fifth Linkage Group of the House Mouse

Abstract

WORK carried out in this Department during the past two years on the fifth linkage group in Mus musculus has established the order circler (kr), agouti (A), undulated (un), wellhaarig (we) and pallid (pa)¹. Recent work also suggests that a gene (pl) modifying the frequency of manifestation of polydactyly is located in this region, possibly between A and pa. Mrs. Wallace², also working in this Department, determined a linkage of the order of 25 per cent recombination between fidget (fi) and Danforth's short tail (Sd). About the same time, Carter and Grüneberg³ ascertained a linkage of about 33.5 per cent recombination between fidget and agouti. Earlier work, both at Cambridge and at the Jackson Memorial Laboratory, Bar Harbor, showed indications of a loose linkage (about 40 per cent recombination) between A and Sd. Thus there was clear evidence of a second series of loci in the order A—fi—Sd.