Abstract
THE fractionation of serum proteins with the aid of quaternary ammonium compounds has met with difficulties, because the detergent/protein ratio must be maintained at a very constant level1. We have shown that this is no longer necessary if ‘Desogen’ (methylphenyl dodecyltrimethyl-ammonium-methosulphate, Geigy S.A., Basle) is used. Separation into at least four components can be performed by the following method.
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References
“Adv. Prot. Chem.”, 4, 79 (1948).
Wiedemann, E., Schweiz. Med. Wschr., 76, 241 (1946).
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LOOMEIJER, F. Fractionation of Serum Proteins with a Quaternary Ammonium Detergent. Nature 166, 951–952 (1950). https://doi.org/10.1038/166951b0
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DOI: https://doi.org/10.1038/166951b0
