Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Amino-acid Composition of Thymus Histone

Abstract

IN the course of our work on the chemistry of the constituents of the cell nucleus, nucleoprotein has been extracted from cell nuclei of normal and tumour tissue and fractionated into three main components: nucleic acid, the basic ‘histone’ protein and an acid-insoluble protein residue1. Quantitative amino-acid analyses are being carried out on these fractions. It was thought that the results obtained for calf thymus histone would be of value, since the results hitherto available account for only 50 per cent of the total composition2.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Mirsky, A. E., and Pollister, A. W., J. Gen. Physiol., 30, 117 (1946).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Greenstein, J. P., “Adv. in Protein Chem.”, 1, 242 (1944).

    Google Scholar 

  3. Moore, S., and Stein, W. H., J. Biol. Chem., 178, 53 (1949).

    CAS  PubMed  Google Scholar 

  4. Rees, M. W., Biochem. J., 40, 632 (1946).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Davidson, J. N., and Lawrie, R. W., Biochem. J., 43, xxix (1948).

    PubMed  Google Scholar 

  6. Kossel, A., “The Protamines and Histones”, 75 (London, 1928).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

HAMER, D. Amino-acid Composition of Thymus Histone. Nature 167, 40 (1951). https://doi.org/10.1038/167040a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/167040a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing