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Specificity of the Enzyme Aconitase

Abstract

BECAUSE the enzyme named ‘aconitase’1 catalyses the conversion of cis-aconitate both to citrate and to isocitrate (and the reverse reactions), it has been thought2 that it may be a mixture of two enzymes, though Buchanan and Anfinsen3 found no evidence of this.

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References

  1. Martius, C., and Knoop, F., Z. physiol. Chem., 246, 1 (1937).

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  2. Jacobsohn, K. P., and Tapadinhas, J., Enzymologia, 5, 388 (1938).

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  3. Buchanan, J. M., and Anfinsen, C. B., J. Biol. Chem., 180, 47 (1949).

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  4. Krebs, H. A., Harvey Lectures, Series xliv, 165 (1950).

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OGSTON, A. Specificity of the Enzyme Aconitase. Nature 167, 693 (1951). https://doi.org/10.1038/167693a0

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