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Use of a Sheep Abortion Virus as a Test Virus for Chemotherapy Work

Abstract

A STRAIN of abortion virus, isolated by us from a local case of sheep abortion in March 1950 and apparently similar to the virus isolated by Stamp, McEwen, Watt and Nisbet1, has been extensively used in an in ovo ‘screening test’. It has proved so satisfactory for this purpose that it is felt its usefulness should be more generally known. The virus in infected membranes remains viable indefinitely at − 20° and for some weeks at 0°, and regularly produces well-defined lesions on the chorioallantoic membrane; in both these respects it is superior to many other large viruses. So far as is known, it is not pathogenic to man.

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References

  1. Stamp, J. T., McEwen, A. D., Watt, J. A. A., and Nisbet, D. I., Vet. Rec., 62, 251 (1950).

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DICKINSON, L., INKLEY, G. Use of a Sheep Abortion Virus as a Test Virus for Chemotherapy Work. Nature 168, 37 (1951). https://doi.org/10.1038/168037a0

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