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Production of Ketoglutarate by Penicillium chrysogenum

Abstract

Krebs and Eggleston1 have isolated ketoglutaric acid (I) during a study of arsenite-inhibited pyruvate utilization by pigeon's breast muscle. Lockwood and Stodola2 have isolated substantial yields of the same compound from a Pseudomonas fluorescens fermentation of glucose. From moulds its isolation has been reported only by Uemura3, who obtained it on deamination of glutamic acid by Aspergillus oryzœ.

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References

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  3. Uemura, T., J. Agric. Chem. Soc. Japan, 15, 353 (1939), from Chem. Abs., 33, 8872 (1939).

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HOCKENHULL, D., WILKIN, G. & WINDER, F. Production of Ketoglutarate by Penicillium chrysogenum. Nature 168, 1043 (1951). https://doi.org/10.1038/1681043a0

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  • DOI: https://doi.org/10.1038/1681043a0

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