Abstract
KAWAI1 converted cholic acid to chenodeoxycholic acid (3α : 7α-dihydroxycholanic acid, anthropodeoxycholic acid) by Kishner–Wolff reduction of the derived 3 : 7-dihydroxy-12-keto cholanic acid. Plattner and Heusser2 similarly reduced methyl 3 : 7-di-acetoxy-12-keto cholanate.
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References
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ANDERSON, I., HASLEWOOD, G., WIGGINS, H. et al. Preparation of Chenodeoxycholic Acid from Cholic Acid. Nature 169, 621 (1952). https://doi.org/10.1038/169621a0
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DOI: https://doi.org/10.1038/169621a0
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