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Intracardiac right-to-left shunting and the risk of stroke during bone marrow infusion

Bone Marrow Transplantation volume 19, pages 855–856 (1997)Cite this article

Abstract

We describe a patient who developed a paradoxical embolus to the brain during infusion of bone marrow. She had a patent foramen ovale through which right-to-left shunting led to multiple cerebral emboli. This complication can be prevented by positioning the tip of the infusion catheter in the main pulmonary artery and reducing the volume of marrow product infused.

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Authors and Affiliations

  1. Division of Pediatric Hematology/Oncology, UCLA School of Medicine, Los Angeles, USA

    TB Moore & SA Feig

  2. Division of Pediatric Cardiology, UCLA School of Medicine, Los Angeles, USA

    VJT Chow

  3. Division of Pediatric Cardiology, UCLA School of Medicine and Cedars-Sinai Medical Center, Los Angeles, CA, USA

    D Ferry

Authors
  1. TB Moore
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  2. VJT Chow
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  3. D Ferry
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  4. SA Feig
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Moore, T., Chow, V., Ferry, D. et al. Intracardiac right-to-left shunting and the risk of stroke during bone marrow infusion. Bone Marrow Transplant 19, 855–856 (1997). https://doi.org/10.1038/sj.bmt.1700742

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  • DOI: https://doi.org/10.1038/sj.bmt.1700742

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