Table 3 Nonrelapse mortality at post-transplant day 100 and 5-year overall survival according to the occurrence of grades III–IV metabolic abnormalities
From: Severe metabolic abnormalities after allogeneic hematopoietic cell transplantation
Patient no. | D100 NRM (%) | P-value a | 5-year OS (%) | P-value a | |
|---|---|---|---|---|---|
Any abnormalities | |||||
Grades 0–2 | 42 (13.5%) | 0 | 0.015 | 78.4 | 0.002 |
Grades 3–4 | 269 (86.5%) | 13.3 | 54.6 | ||
Hypophosphatemia | |||||
Grades 0–2 | 206 (66.2%) | 8.9 | 0.042 | 60.0 | 0.006 |
Grades 3–4 | 105 (33.8%) | 16.9 | 48.8 | ||
Hyperkalemia | |||||
Grades 0–2 | 286 (92.0%) | 8.9 | <0.001 | 59.9 | <0.001 |
Grades 3–4 | 25 (8.0%) | 42.0 | 32.5 | ||
Hypokalemia | |||||
Grades 0–2 | 162 (52.1%) | 5.7 | 0.001 | 67.0 | <0.001 |
Grades 3–4 | 149 (47.9%) | 17.8 | 47.0 | ||
Hypernatremia | |||||
Grades 0–2 | 298 (95.8%) | 9.2 | <0.001 | 59.6 | <0.001 |
Grades 3–4 | 13 (4.2%) | 68.5 | 15.4 (3 years) | ||
Hyponatremia | |||||
Grades 0–2 | 126 (40.5%) | 4.8 | 0.004 | 69.1 | 0.001 |
Grades 3–4 | 185 (59.5%) | 16.1 | 49.8 | ||
Hypermagnesemia | |||||
Grades 0–2 | 302 (97.1%) | 9.8 | <0.001 | 58.7 | <0.001 |
Grades 3–4 | 9 (2.9%) | 66.7 | 22.2 (4 years) | ||
Hypomagnesemia | |||||
Grades 0–2 | 259 (83.3%) | 12.3 | 0.358 | 58.9 | 0.497 |
Grades 3–4 | 52 (16.7%) | 7.8 | 52.0 | ||
Hyperglycemia | |||||
Grades 0–2 | 173 (55.6%) | 3.5 | <0.001 | 62.1 | <0.001 |
Grades 3–4 | 138 (44.4%) | 21.7 | 48.4 | ||
Hypoglycemia | |||||
Grades 0–2 | 299 (96.1%) | 11.3 | 0.633 | 57.9 | 0.964 |
Grades 3–4 | 12 (3.9%) | 16.7 | 53.3 | ||
Hyperuricemia | |||||
Grades 0–2 | 289 (92.9%) | 10.9 | 0.264 | 59.0 | 0.053 |
Grades 3–4 | 22 (7.1%) | 19.1 | 41.8 | ||
