Table 2 Patient and transplant characteristics of neuro(+) patients

From: Life-threatening neurological complications after bone marrow transplantation in children

Pt no.

Age (years)/sex

Primary disease

Pretransplant neurological status

Transplant type

Preparative regimen

GvHD prophylaxis

Engraftment

 1

16/F

AML(relapse)

Normal

HLA 6/6 sibling BM

BuCy/AraC

CsA/MTX

+

 2

7/F

GLD(advanced)

Vegetative state

HLA 5/6 unrelated cord

BuCy/ATG

CsA/MTX

+

 3

11/M

AML(CR2)

Normal

HLA 5/6 father PBSC

Bu/Mel/ATG

CsA

+

 4

5/M

T.Major(class III)

Normal

HLA 6/6 sibling BM

BuCy

CsA/MTX

+

 5

5.5/M

AML(relapse)

Normal

HLA 6/6 sibling BM

BuCy/Mel

CsA

+

 6

8/M

AML nonremission(+SCID)

Normal

HLA 6/6 father PBSC

BuCy

CsA/MTX

+

 7

16/M

AML(relapse)

Normal

HLA 4/6 father BM

BuCy/Mel/ATG

CsA/MTX/MPZ

+

 8

11/M

T.Major(class III)

Normal

HLA 6/6 sibling BM/PBSC

Flu/BuCy

CsA/MTX

+

 9

13/M

FAA(aplastic)

Normal

HLA 6/6 sibling BM

BuaCy20

CsA/MTX

+

10

2/F

Omenn syndrome

Normal

HLA 5/6 mother PBSC

Flu/ATG

CsA

+

11

13/M

FAA(aplastic)

Normal

HLA 6/6 sibling PSBC

Bua/Cy20

CsA

+

  1. aLow dose.
  2. BU=busulphan; AraC=cytarabine; CY=cyclophosphamide; MTX=methotrexate; Flu=fludarabin; CsA=cyclosporine A; Mel=melphalan; FAA=Fanconi aplastic anemia; AML=acute myelogenous leukemia; GLD=globoid cell leukodystrophy; ATG=antithymocyte globulin; SCID=severe combined immune deficiency; MPZ=methyl prednisolone; CR=complete remission.