Table 1 Summary of the incidence of acute and chronic GVHD, and rates of treatment-related mortality and response in studies of stem cell transplantation for metastatic RCC

From: The future of allogeneic hematopoietic stem cell transplantation for metastatic renal cell carcinoma in the era of target-specific therapy

Study

Number of patients

Acute GVHD number (%)

Chronic GVHD number (%)

TRM rate number (%)

Response rate number (%)

Childs et al.3, 4

19

10 (53)

4 (21)

2 (11)

10 (53)

Pedrazzoli et al.5

8

0

0

2 (25)

0

Bregni et al.6

7

6 (86)

5 (71)

1 (14)

4 (57)

Hentschke et al.7

10

5 (50)

3 (30)

3 (30)

3 (30)

Baron et al.8

7

3 (43)

1 (14)

0

1 (14)

Aoyama et al.19

2

1 (50)

0

0

1 (50)

Ueno et al.9

15

7 (47)

4 (27)

5 (33)

3 (20)

Blaise et al.10

25

4 (17)

7 (28)

No data

2 (8)

Bornhauser et al.20

1

1 (100)

1 (100)

1 (100)

1 (100)

Takami et al.21

3

2 (67)

2 (67)

2 (67)

2 (67)

Nakagawa et al.11

9

3 (33)

4 (44)

0

1 (11)

Massenkeil et al.12

7

2 (29)

4 (57)

1 (14)

2 (29)

Tykodi et al.13

8

4 (50)

4 (50)

1 (13)

1 (13)

Secondino et al.22

1

1 (100)

1 (100)

1 (100)

1 (100)

Rini et al.14, 15; Artz et al.16

18

3 (17)

7 (39)

6 (33)

4 (22)

Rzepecki et al.17

5

3 (60)

0

0

0

Rini et al. (CALGB)18

22

11 (50)

5 (23)

2 (9)

0

  1. Abbreviations: GVHD=graft-versus-host disease; RCC=renal cell carcinoma; TRM=treatment-related mortality.