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Relation between Total and Exchangeable Sodium in the Body

Nature volume 170, page 979 (1952)Cite this article

Abstract

EARLY workers, who studied the fate of sodium-24 administered to animals, showed that the isotope exchanged with the sodium of the tissues1. They assumed that all the body sodium participated in this exchange. That this assumption is incorrect was suggested by recent results obtained with dogs2 and humans3–5, in which 20–35 per cent of the body sodium was estimated to be non-exchangeable with plasma sodium-24.

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References

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Author notes

  1. H. L. KORNBERG: John Stokes Research Fellow.

Authors and Affiliations

  1. Medical Research Council Cell Metabolism Research Unit, Department of Biochemistry, University, Sheffield,

    R. E. DAVIES & H. L. KORNBERG

  2. Department of Pharmacology and Therapeutics, University, Sheffield,

    G. M. WILSON

Authors
  1. R. E. DAVIES
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  2. H. L. KORNBERG
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  3. G. M. WILSON
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DAVIES, R., KORNBERG, H. & WILSON, G. Relation between Total and Exchangeable Sodium in the Body. Nature 170, 979 (1952). https://doi.org/10.1038/170979a0

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