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A Browning Reaction between Thiamine and Glucose

Abstract

DURING some experiments on the non-enzymatic browning reaction between reducing sugars and nitrogenous compounds, it was found that a mixture of glucose and thiamine-hydrochloride showed considerable browning when heated in sealed glass tubes at 85° C. for some days. The experiment was repeated on a larger scale and the results seem worth publication.

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References

  1. Gottschalk, A., and Partridge, S. M., Nature, 165, 684 (1950).

    Article  ADS  CAS  Google Scholar 

  2. Haas, V. A., Stadtman, F. R., Stadtman, F. H., and MacKinney, G., J. Amer. Chem. Soc., 70, 3576 (1948).

    Article  CAS  Google Scholar 

  3. Patton, A. R., and Hill, E. G., Science, 107, 68 (1948).

    Article  ADS  CAS  Google Scholar 

  4. Menger, A., Brot und Gebäck, 6, 89 (1953).

    Google Scholar 

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DE LANGE, P., DEKKER, L. A Browning Reaction between Thiamine and Glucose. Nature 173, 1040–1041 (1954). https://doi.org/10.1038/1731040a0

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