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Effect of Acetate on the Fasting Blood-Sugar Level of the Rat

Abstract

Chari and Wertheimer1 state that intraperitoneal injection of acetate (100 mgm./100 gm. body weight?) into rats “caused hypoglycæmia and increased alkalosis” but give no details of their experiments. In view of the known interrelationship between glucose and acetate in the ruminant2, it was considered of interest to investigate this point further.

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References

  1. Chari, A., and Wertheimer, E., Nature, 171, 44 (1953).

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  2. Reid, R. L., Aust. J. Agric. Res., 1, 338 (1950).

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  3. Parnes, J., and Wertheimer, E., Biochem. J., 46, 517, 520 (1950).

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  4. Garner, R. J., and Roberts, R. (unpublished results).

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GARNER, R., ROBERTS, R. Effect of Acetate on the Fasting Blood-Sugar Level of the Rat. Nature 174, 1194–1195 (1954). https://doi.org/10.1038/1741194a0

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