Use of Mercurated Thiazoles as Fungistatic Agents

Abstract

IN the course of our studies on methods of synthesis of thiazole derivatives and their possible useful applications, it appeared of interest to examine their fungicidal properties, since these contain in a cyclic ring structure the grouping N—C—S which is present in known fungicides like tetramethyl thiuram disulphide, thioureas and thioacetamide. Some new mercurated derivatives of thiazoles have also been prepared by us, and since mercury is a powerful fungicidal element, phenyl mercuric acetate being actually used for such diseases as apple scab, it was considered worth while to test these mercurated thiazoles for their fungicidal action.