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Intracellular Distribution of Histamine
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  • Letter
  • Published: 09 October 1954

Intracellular Distribution of Histamine

  • I. MOTA1,
  • W. T. BERALDO1,
  • A. G. FERRI1 &
  • …
  • L. C. U. JUNQUEIRA1 

Nature volume 174, page 698 (1954)Cite this article

  • 631 Accesses

  • 70 Citations

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Abstract

ALTHOUGH histamine is widely distributed in the tissues, very little has been reported on its intracellular distribution. Recently, Copenhaver et al. 1 and Hagen2, studying the histamine content of different cell fractions of dog liver, verified that the major amount of this substance was present in the mitochondrial fraction.

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References

  1. Copenhaver, J. H., Nagler, M. E., and Goth, A., J. Pharm. Exp. Therapy, 109, 401 (1953).

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  2. Hagen, P., Brit. J. Pharmacol. Chemotherapy, 9, 100 (1954).

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  3. Michels, N. A., in Downey, H., “Handbook of Hematology”, 1 (Paul Hoeber, Inc., New York, 1938).

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  4. Schneider, W. C., in “Manometric Techniques and Tissue Metabolism” (Burgess Publishing Co., 1951).

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  5. Riley, J. F., and West, G. B., J. Physiol., 120, 528 (1953). Riley, J. F., Science, 118, 332 (1953).

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  6. Wilander, O., Skand. Arch. Physiol., 81, Supp. xv (1939). Jaques, L. S., and Waters, E. T., J. Physiol., 99, 454 (1941). Mota, I., thesis, University of São Paulo (1953). Riley, J. F., J. Path. Bact., 65, 471 (1953). Mota, I., Beraldo, W. T., and Junqueira, L. C. U., Proc. Soc. Exp. Biol. Med., 83, 455 (1953). Benditt, E. P., Bader, S., Arase, M., Corley, C., and Lam, K. B., Fed. Proc., 13, 422 (1954).

    Google Scholar 

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Author information

Authors and Affiliations

  1. Laboratory for Cell Physiology and Department of Physiology, Faculty of Medicine, Department of Pathology, Faculty of Veterinary Medicine, University of São Paulo,

    I. MOTA, W. T. BERALDO, A. G. FERRI & L. C. U. JUNQUEIRA

Authors
  1. I. MOTA
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  2. W. T. BERALDO
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  3. A. G. FERRI
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  4. L. C. U. JUNQUEIRA
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Cite this article

MOTA, I., BERALDO, W., FERRI, A. et al. Intracellular Distribution of Histamine. Nature 174, 698 (1954). https://doi.org/10.1038/174698a0

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  • Issue date: 09 October 1954

  • DOI: https://doi.org/10.1038/174698a0

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