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Chemical Composition of the Melanin Granule and its Relation to the Mitochondrion

Abstract

IT has been suggested that the melanin-containing granules of melanocytes are derived from the mitochondria of these cells. The term ‘melanized mitochondria’ has been used for describing the melanin granules1. The main evidence to support this contention has been the demonstration of the presence in both mitochondria and melanin granules of the enzymes succinic dehydrogenase and cytochrome oxidase.

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STEIN, W. Chemical Composition of the Melanin Granule and its Relation to the Mitochondrion. Nature 175, 256–257 (1955). https://doi.org/10.1038/175256a0

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